The CIBERSAM is a cooperative networking structure formed by 24 groups located in some of the most important main research in Spain and the Gregorio Marañón General Hospital of Madrid (HGUGM) is the largest university hospital in Spain. The Child and Adolescent Psychiatry Department at the HGUMG, headed by Dr. Celso Arango and one of the groups of CIBERSAM (Group 001), has extensive experience conducting both private and non-profit clinical trials and research projects in affective disorders, psychosis, and autism. Researchers from Gregorio Marañón General Hospital have long been conducting research on psychiatric disorders in children and adolescents. Among others, they have been participating in several studies of children and adolescents with psychosis, autism spectrum disorder, and affective disorders. They have conducted research in areas including clinical, neuropsychological, neuroimaging, and genetic evaluations, with high research standards in all domains, corroborated by scientific publication of their findings in high impact journals. The Department is composed by 12 clinicians (part-time) and 20 research fellows (full-time dedicated to research), trained on clinical and cognitive assessments in neurodevelopmental disorders.
Radboud university medical center is one of eight university medical centers in The Netherlands. With nearly 9,000 employees and 3,000 students, Radboudumc combines patient care, research, and education/training. The department of Human Genetics within the Radboudumc is an internationally top-ranking genetics group and among the largest centre for genetics research, clinical diagnostics and genetic counselling in Europe.
Neuroscience research in Nijmegen is concentrated in the Donders Institute for Brain, Cognition and Behaviour. The Donders Institute is a world-renowned centre of neuroscience research expertise. We are a relatively young institute with an enterprising spirit and an excellent track record of research on Brain, Cognition and Behaviour. Over 500 researchers work here on unravelling the mechanisms of the brain. Our research includes cognition and behaviour in humans as well as on the neuronal substrate, including the genetic, molecular and cellular processes that underlie cognition and behaviour. We cover the full spectrum of research ‘from Molecule to Man’.
P1vital® is an innovative Clinical Research Organization specializing in experimental medicine for Central Nervous System (CNS) disorders.
We aim to develop and deploy CNS efficacy biomarkers in schizophrenia, cognitive disorders, depression and anxiety, eating disorders, and obesity – with the aim of instigating innovative approaches to, and accelerating, drug discovery.
Our team has extensive expertise in all aspects of CNS drug discovery and development, including regulatory and compliance expertise. We are also skilled in running multi-centred academic behavioural and imaging experimental medicine studies (in all clinical phases) that require subjects with unique phenotypes.
We have a strong track record of collaborating with internationally renowned opinion leaders in psychiatry and neuroscience, linked through University hospitals and clinical research facilities worldwide.
The Groningen Institute of Evolutionary Life Sciences (GELIFES) fills a special niche in the field of life sciences that not only covers mechanistic, evolutionary and ecological approaches, but also specifically aims at the integration of these fields to provide a full understanding of fundamental biological processes. Evolution on a long time scale has shaped the regulatory mechanisms acting on short time scales that determine the potential and limitations of adaptive capacity. This is relevant for understanding the prevalence and treatment of diseases, including neuropsychiatric disorders, as well as individual differences in aging and health that determine the scope for personalized medicine. In turn, the nature of these mechanisms determines the potential, direction, speed, and limitation of evolutionary change. This is important, e.g. for understanding speciation and changes in biodiversity, predicting effects of global change, and brain adaptations to cope with environmental challenges.